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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. | |||
T1406 | Amantadine hydrochloride | 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride | Dopamine Receptor , Influenza Virus |
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease. | |||
T34435 | RU 47213 | RU-47213,Itameline,RU47213 | Others |
RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats. | |||
TN2230 | Soyasaponin Ba | Others | |
Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ... | |||
T77678 | TZ3O | AChR | |
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ... | |||
T4956 | Tetrahydroxystilbene-2-O-β-D-glucoside | tetrahydroxyl diphenylethylene-2-o-gluco,EH-201 | Others |
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc... | |||
TP1570 | Cortistatin-14 | Somatostatin | |
Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, has anticonvulsant and neuroprotective effects and impairs recognition memory consolidation in mice through activation of sst(2), growth hormone... | |||
T5702 | Tenuifoliside B | Dehydrogenase | |
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi... | |||
T6S2227 | Spinosin | Flavoayamenin | Others |
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato... | |||
T21792 | CGP 3466B maleate | Omigapil (Maleate),Omigapil maleate | Apoptosis |
CGP 3466B maleate (Omigapil maleate) is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil male... | |||
T62899 | Tau-aggregation and neuroinflammation-IN-1 | Microtubule Associated , NO Synthase | |
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma... | |||
T38192 | Unifiram | Others | |
Unifiram is a nootropic agent.1It increases acetylcholine (ACh) release in the rat cerebral cortexin vivoand induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the ra... | |||
T33424 | MK-0952 | MK 0952 | |
MK-0952 is a selective PDE4 inhibitor used to treat long-term memory loss and mild cognitive impairment. It is an intrinsically potent inhibitor and has shown limited whole blood activity. | |||
T69314 | T-82 | ||
T-82 is an acetylcholinesterase inhibitor that may ameliorate the impairment of memory induced by acetylcholinergic dysfunction. | |||
T39384 | Exendin (5-39) | ||
Exendin (5-39) is a powerful antagonist of the glucagon-like peptide 1 (GLP-1) receptor with the ability to ameliorate memory impairment in rats treated with β-amyloid protein. | |||
T21470 | Davunetide | AL-208,AL 208,AL 108,AL-108 | |
Davunetide is an eight amino acid peptide (NAPVSIPQ) with potent neuroprotection in vitro and in vivo. Davunetide has been shown to enhance functional daily behaviors in schizophrenia patients and to increase memory scor... | |||
T61684 | S 17092 | ||
S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorder... | |||
T64672 | Colivelin TFA | ||
Colivelin (sequence SALLRSIPAPAGASRLLLLTGEIDLP) is composed of activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA-(C8R)HNG17, a potent HN derivative. It works as a neuroprotective peptide and activat... | |||
T80071 | PKCζ/ι pseudosubstrate inhibitor | ||
PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of memory impairment [1]. | |||
T28653 | S-8510 free base | SB 737552,SB-737552,S8510,SB737552,S-8510,S 8510 | |
S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ame... |